References

Aghajafari F, Letourneau N, Mahinpey N, Cosic N, Giesbrecht G. Vitamin D deficiency and antenatal and postpartum depression: a systematic review. Nutrients. 2018; 10:(4) https://doi.org/10.3390/nu10040478

Aji AS, Erwinda E, Yusrawati Y, Malik SG, Lipoeto NI. Vitamin D deficiency status and its related risk factors during early pregnancy: a cross-sectional study of pregnant Minangkabau women, Indonesia. BMC pregnancy and Childbirth. 2019; 19:(1) https://doi.org/10.1186/s12884-019-2341-4

Al-Yatama FI, AlOtaibi F, Al-Bader MD, Al-Shoumer KA. The effect of clothing on vitamin d status, bone turnover markers, and bone mineral density in young Kuwaiti females. International Journal of Endocrinology. 2019; https://doi.org/10.1155/2019/6794837

Bonevski B, Bryant J, Lambert S, Brozek I, Rock V. The ABC of vitamin D: a qualitative study of the knowledge and attitudes regarding vitamin D deficiency amongst selected population groups. Nutrients. 2013; 5:(3)915-927 https://doi.org/10.3390/nu5030915

Cannell J. Best natural sources of vitamin D. Alternative Medicine. 2019; (44)26-27

Carrelli A, Bucovsky M, Horst R, Cremers S, Zhang C, Bessler M, Schrope B, Evanko J, Blanco J, Silverberg SJ, Stein EM. Vitamin D storage in adipose tissue of obese and normal weight women. Journal of Bone and Mineral Research. 2017; 32:(2)237-242 https://doi.org/10.1002/jbmr.2979

Chen B, Ji X, Zhang L, Hou Z, Li C, Tong Y. Fish oil supplementation improves pregnancy outcomes and size of the newborn: a meta-analysis of 21 randomized controlled trials. The Journal of Maternal-Fetal and Neonatal Medicine. 2016; 29:(12)2017-2027 https://doi.org/10.3109/14767058.2015.1072163

Chen Y, Zhu B, Wu X, Li S, Tao F. Association between maternal vitamin D deficiency and small for gestational age: evidence from a meta-analysis of prospective cohort studies. BMJ Open. 2017; 7:(8) https://doi.org/10.1136/bmjopen-2017-016404

Davies-Tuck M, Yim C, Knight M, Hodges R, Doery JC, Wallace E. Vitamin D testing in pregnancy: does one size fit all?. AZJOG. 2015; 55:(2)149-155 https://doi.org/10.1111/ajo.12278

Clinical practice guidelines: pregnancy care.Canberra: Australian Government Department of Health; 2018

De-Regil LM, Palacios C, Lombardo LK, Peña-Rosas JP. Vitamin D supplementation for women during pregnancy. Cochrane Systematic Review - Intervention. 2016; https://doi.org/10.1002/14651858.CD008873.pub3

De Laine KM, Matthews G, Grivell RM. Prospective audit of vitamin D levels of women presenting for their first antenatal visit at a tertiary centre. AZJOG. 2013; 53:(4)353-357 https://doi.org/10.1111/ajo.12052

Divakar H, Singh R, Narayanan P, Divakar G. Prevalence of vitamin D deficiency and the impact of oral supplementation in an unselected pregnant Indian population. Journal of Evidence Based Medicine and Healthcare. 2018; 5:(52)3589-3592 https://doi.org/10.18410/jebmh/2018/731

Fallon EL, Lanham-New SA, Williams P, Ray S. An investigation of the vitamin D knowledge, attitudes and practice of UK practising doctors and nurses: the D-KAP study. Proceedings of the Nutrition Society. 2020; 79:(OCE1) https://doi.org/10.1017/S0029665119001411

Fischer K. Vitamin D principles of nutrigenetics and nutrigenomics. Fundamentals of Individualized Nutrition. 2020; 245-254 https://doi.org/10.1016/B978-0-12-804572-5.00032-X

González-Chica D, Stocks N. Changes to the frequency and appropriateness of vitamin D testing after the introduction of new medicare criteria for rebates in Australian general practice: evidence from 1.5 million patients in the NPS MedicineInsight database. BMJ Open. 2019; 9 https://doi.org/10.1136/bmjopen-2018-024797

Griffiths JK. Vitamin deficiencies: Hunter's tropical medicine and emerging infectious diseases. 2020; 1042-1047

Hasanpour Dehkordi A. Vitamin D and population health; a nephrology viewpoint. Journal of Nephropathology. 2018; 7:(3) https://doi.org/10.15171/jnp.2018.27

Hynes C, Jesurasa A, Evans P, Mitchell C. Vitamin D supplementation for women before and during pregnancy: an update of the guidelines, evidence, and role of GPs and practice nurses. British Journal of General Practice. 2017; 67:(662)423-424 https://doi.org/10.3399/bjgp17X692489

Vitamin D: its role in the musculoskeletal system and beyond. 2017. https://www.um.edu.mt/library/oar/handle/123456789/26956

Malacova E, Cheang PR, Dunlop E, Sherriff JL, Lucas RM, Daly RM, Nowson CA, Black LJ. Prevalence and predictors of vitamin D deficiency in a nationally representative sample of adults participating in the 2011–2013 Australian Health Survey. British Journal of Nutrition. 2019; 121:(8)894-904 https://doi.org/10.1017/S0007114519000151

Middleton P, Gomersall JC, Gould JF, Shepherd E, Olsen SF, Makrides M. Omega-3 fatty acid addition during pregnancy. Cochrane Systematic Review - Intervention. 2018; (11) https://doi.org/10.1002/14651858.CD003402.pub3

Mir SA, Masoodi SR, Shafi S, Hameed I, Dar MA, Bashir MI, Wani AI, Shah ZA, Parveen S, Zargar AH, Shah PA. Efficacy and safety of vitamin D supplementation during pregnancy: a randomized trial of two different levels of dosing on maternal and neonatal vitamin D outcome. Indian Journal of Endocrinology and Metabolism. 2016; 20:(3) https://doi.org/10.4103/2230-8210.179991

Mitchell BL, Zhu G, Medland SE, Renteria ME, Eyles DW, Grasby KL, McGrath JJ, Martin NG. Half the genetic variance in vitamin D concentration is shared with skin colour and sun exposure genes. Behavior Genetics. 2019; 49:(4)386-398 https://doi.org/10.1007/s10519-019-09954-x

Naqvi A, Solomons NW, Campos R, Soto-Méndez MJ, Caplan E, Armas L, Bermudez OI. Vitamin D status among indigenous Mayan (Kekchi) and Afro-Caribe (Garifuna) adolescents from Guatemala: a comparative description between two ethnic groups residing on the Rio Dulce at the Caribbean coast in Izabal Province, Guatemala. Public Health Nutrition. 2017; 20:(10)1729-1737 https://doi.org/10.1017/S1368980016000598

National Diet and Nutrition Survey. National Diet and Nutritional study: time, trend and income analyses for years 1 to 9. 2019. https://www.gov.uk/government/statistics/ndns-time-trend-and-income-analyses-for-years-1-to-9 (accessed 1 December 2019)

O'Brien CM, Grivell RM, Dodd JM. Systematic review of antenatal dietary and lifestyle interventions in women with a normal body mass index. Acta Obstetricia et Gynecologica Scandinavica. 2016; 95:(3)259-269 https://doi.org/10.1111/aogs.12829

Palacios C, Kostiuk LK, Peña-Rosas JP. Vitamin D supplementation for women during pregnancy. Cochrane Systematic Review - Intervention. 2019a; https://doi.org/10.1002/14651858.CD008873.pub4

Palacios C, Trak-Fellermeier MA, Martinez RX, Lopez-Perez L, Lips P, Salisi JA, John JC, Peña-Rosas JP. Regimens of vitamin D supplementation for women during pregnancy. Cochrane Systematic Review - Intervention. 2019b; https://doi.org/10.1002/14651858.CD013446

Patil S, Tripathi S, Shah S. Evaluation of effect of vitamin D supplementation on vitamin D levels and pregnancy outcome. Indian Journal of Obstetrics and Gynecology Research. 2018; 5:(3)344-348 https://doi.org/10.18231/2394-2754.2018.0079

Paxton GA, Teale GR, Nowson CA, Mason RS, McGrath JJ, Thompson MJ, Siafarikas A, Rodda CP, Munns CF. Vitamin D and health in pregnancy, infants, children and adolescents in Australia and New Zealand: a position statement. Medical Journal of Australia. 2013; 198:(3)142-143 https://doi.org/10.5694/mja11.11592

Porter CM, Wechsler AM, Hime SJ, Naschold F. Adult health status among Native American families participating in the growing resilience home garden study. Preventing Chronic Disease. 2019; https://doi.org/10.5888/pcd16.190021

Richard A, Rohrmann S, Quack Lötscher KC. Prevalence of vitamin D deficiency and its associations with skin color in pregnant women in the first trimester in a sample from Switzerland. Nutrients. 2017; 9:(3) https://doi.org/10.3390/nu9030260

Roth DE, Leung M, Mesfin E, Qamar H, Watterworth J, Papp E. Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials. BMJ. 2017; 359 https://doi.org/10.1136/bmj.j5237

Royal College of Obstetricians and Gynaecologists. Vitamin D in Pregnancy. Scientific Impact Paper no. 43, June 2014, 1-11. 2014. 2014. https://www.rcog.org.uk/globalassets/documents/guidelines/scientific-impact-papers/vitamin_d_sip43_june14.pdf (accessed 1 December 2019)

Sanders R, Lamb K. Promoting vitamin D uptake in pregnancy and the puerperium. British Journal of Midwifery. 2015; 23:(7)5-9 https://doi.org/10.12968/bjom.2015.23.Sup7.5

Shah J, Gurbani S. Association of vitamin D deficiency and mood disorders: a systematic review. IntechOpen. 2019; https://doi.org/10.5772/intechopen.90617

Shao B, Mo M, Xin X, Jiang W, Wu J, Huang M, Wanga S, Muyidulia X, Sia S, Shena Y, Chena Z, Yu Y. The interaction between prepregnancy BMI and gestational vitamin D deficiency on the risk of gestational diabetes mellitus subtypes with elevated fasting blood glucose. Clinical Nutrition. 2019; https://doi.org/10.1016/j.clnu.2019.10.015

Skaaby T, Husemoen LLN, Thuesen BH, Pisinger C, Hannemann A, Jørgensen T, Linneberg A. Longitudinal associations between lifestyle and vitamin D: a general population study with repeated vitamin D measurements. Endocrine. 2016; 51:(2)342-350 https://doi.org/10.1007/s12020-015-0641-7

Tang H, Li D, Li Y, Zhang X, Song Y, Li X. Effects of vitamin D supplementation on glucose and insulin homeostasis and incident diabetes among nondiabetic adults: a meta-analysis of randomized controlled trials. International journal of endocrinology. 2018; 2018 https://doi.org/10.1155/2018/7908764

Wagner CL, Hollis BW. The implications of vitamin D status during pregnancy on mother and her developing child. Frontiers in Endocrinology. 2018; 9 https://doi.org/10.3389/fendo.2018.00500

Wang H, Xiao Y, Zhang L, Gao Q. Maternal early pregnancy vitamin D status in relation to low birth weight and small-for-gestational-age offspring. The Journal of Steroid Biochemistry and Molecular Biology. 2018; 175:146-150 https://doi.org/10.1016/j.jsbmb.2017.09.010

Weinert LS, Silveiro SP Maternal–fetal impact of vitamin D deficiency: a critical review. Maternal and Child Health Journal. 2015; 19:(1)94-101 https://doi.org/10.1007/s10995-014-1499-7

Wimalawansa SJ. Associations of vitamin D with insulin resistance, obesity, type 2 diabetes, and metabolic syndrome. Journal of Steroid Biochemistry and Molecular Biology. 2018a; 175:177-189 https://doi.org/10.1016/j.jsbmb.2016.09.017

Wimalawansa SJ. Vitamin D and cardiovascular diseases: causality. Journal of Steroid Biochemistry and Molecular Biology. 2018b; 175:29-43 https://doi.org/10.1016/j.jsbmb.2016.12.016

World Health Organization. Recommendation regarding Vitamin D supplementation during pregnancy. 2016. https://extranet.who.int/rhl/topics/preconception-pregnancy-childbirth-and-postpartum-care/antenatal-care/who-recommendation-regarding-vitamin-d-supplementation-during-pregnancy (accessed 1 December 2019)

Importance of vitamin D during the antenatal period for maternal well-being

02 June 2020
Volume 28 · Issue 6
 Fish oil supplements are recommended as a good source of vitamin D
Fish oil supplements are recommended as a good source of vitamin D

Abstract

Vitamin D deficiency is widely recognised as a major public health issue around the world; and is essential for optimal development and strengthening of the musculoskeletal system including the prevention of conditions such as osteoporosis, osteopenia and rickets. The association between vitamin D and childhood rickets has led to the fortification of food sources and consequently the eradication of the rickets disease. Vitamin D levels are of particular importance for pregnant women, especially for the development of the bone and muscle development of the fetus. In the last decade there has been a substantial increase in the incidence of vitamin D deficiency and the re-emergence of the childhood rickets disease. It is vital that vitamin D levels are at optimal levels during pregnancy as maternal calcium demands increase significantly to meet the demands of the developing fetus, especially in the third trimester.

The best source of vitamin D is exposure to natural sunlight and 90% of vitamin D is derived from sunlight with 10% derived from food and plant sources (Paxton et al, 2013; Cannell, 2019). Approximately 1 in 5 people have low vitamin D levels (defined as serum levels below 25 nmol/L) in the UK. Recent statistics reveal that vitamin D deficiency affects the population as follows: 19% aged 4–10 years old, 37% 11–18 years old, 29% 19–64 years old, and 27% for people aged 65 years and older (National Diet and Nutrition Survey, 2019). There is sufficient research to support a correlation between certain risk factors and vitamin D deficiency including lack of exposure to sunlight, darker skin pigmentation, increased body mass index and certain ethnic groups which involves the wearing of cultural garments (Paxton et al, 2013; Fallon et al, 2020).

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